C: Use with caution if Advantages outweigh risks. Animal research display danger and human studies not readily available or neither animal nor human studies completed.
Question your medical doctor Should you have questions on varieties of start Manage which will give you the results you want. For those who or your spouse come to be Expecting when utilizing bortezomib or for 7 months soon after your remaining dose, call your medical professional straight away.
armodafinil will reduce the extent or outcome of bortezomib by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Keep an eye on.
Indicated for retreatment of adults with numerous myeloma who experienced Earlier responded to bortezomib and relapsed not less than six months subsequent completion of prior bortezomib remedy
acetazolamide will raise the amount or result of bortezomib by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Small/Significance Unfamiliar.
triclabendazole will raise the level or influence of bortezomib by affecting hepatic enzyme CYP2C19 metabolism.
dexamethasone will lessen the level or effect of bortezomib by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Check.
Keep track of Carefully (one)voriconazole will boost the amount or result of bortezomib by influencing hepatic/intestinal enzyme CYP3A4 metabolism.
apalutamide will decrease the level or outcome of bortezomib by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Stay clear of or Use Alternate Drug. Coadministration of apalutamide, a powerful CYP3A4 inducer, with prescription drugs which might Lin281632 be CYP3A4 substrates can lead to decreased publicity to these drugs.
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pentobarbital will lessen the level or outcome of bortezomib by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Keep track of.
The drug is metabolized by the CYP3A4 and CYP2C19 enzymes within the liver. The Dup 747 metabolites Lp-PLA2-IN-1 are inactive and are excreted through the kidney.
fedratinib will raise the stage or outcome of bortezomib by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Check. Change dose of medicine that are CYP3A4 substrates as required.
erythromycin stearate will enhance the amount or outcome of bortezomib by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Keep an eye on.